马昕
最后学位:东南大学工学博士
岗位职称:副教授
研究领域:生物信息学
教学课程:微积分、线性代数、概率论与数理统计
办公室:竞慧西楼410
电 话:86-025-58318699
Emai l :maxin@nau.edu.cn
通讯地址:南京市浦口区雨山西路86号
邮 编:211815
学习简历
1999.09 – 2003.06 苏州大学数学科学学院 数学与应用数学专业 理学学士
2003.09 – 2006.06 苏州大学数学科学学院 应用数学专业 理学硕士
2008.09 – 2012.09 东南大学生物医学工程学院 生物医学工程专业 工学博士
工作简历
2006.06 - 2008.10南京审计大学助教
2008.10-2014.07南京审计大学 讲师
2014.07 –现在南京审计大学 副教授
主持参与课题
1. DNA\RNA相互结合的蛋白质预测与统计分析,国家自然科学基金,项目批准号:61305072(主持人)
2. 基于机器学习算法的SmallRNA-结合位点预测,江苏省高校自然科学研究计划项目,项目批准号:14KJB520020(主持人)
3. 基于序列的蛋白质与DNA相互作用的预测研究,江苏省高校自然科学研究计划项目,项目批准号:12KJD520006(主持人)
4. 支持向量机和随机森林算法在海量数据分析中的应用,南京审计大学校级课题,项目批准号:NSK2009/01(主持人)
5. 人类基因组遗传变异与核小体定位的相互作用研究,国家自然科学基金,项目批准号:31240080(参与,4/8)
6. 核小体定位的动态调控信息分析,国家自然科学基金,项目批准号:61073141(参与,6/10)
7. 动态核小体定位及其在癌细胞中的基因调节作用研究,江苏省自然科学基金面上项目,项目批准号:BK2010406(参与,9/9)
科研成果
1、Xin Ma*, Jing Guo and Xiao Sun, DNABP: Identification of DNA-binding proteins based on feature selection using a random forest and predicting binding residues, PLoS ONE, 11(12):e0167345, 2016. (SCI)
2、Xin Ma*, Jing Guo, Ke Xiao and Xiao Sun,PRBP: Prediction of RNA-binding proteins using a random forest algorithm combined with an RNA-binding residue predictor, IEEE/ACM Transactions on Computational Biology and Bioinformatics,12(6),1385-1393,2015. (SCI)
3、Xin Ma*, Jing Guo and Xiao Sun Sequence-Based Prediction of RNA-Binding Proteins Using Random Forest with Minimum Redundancy Maximum Relevance Feature Selection,BioMed Research International, volume 2015, Article ID 425810, 10 page http://dx.doi.org/10.1155/2015/425810, 2015. (SCI)
4、Xin Ma* and Xiao Sun,Sequence-based predictor of ATP-binding residues using random forest and mRMR-IFS feature selection, Journal of Theoretical Biology, 360: 59-66, 2014. (SCI)
5、Xin Ma*, Jian-Sheng Wu and Xiao-Yun Xue, Identification of DNA-binding proteins using support vector machine with sequence information, Computational and Mathematical Methods in Medicine,2013:524502, doi: 10.1155/2013/524502, 2013. (SCI)
6、Xin Ma, Jing Guo, Hong-De Liu, Jian-Ming Xie and Xiao Sun*,Sequence-based prediction of DNA-binding residues in proteins with conservation and correlation information, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 41(2), 213-224, 2012. (SCI)
7、Xin Ma, Jing Guo, Jian-Sheng Wu, Hong-De Liu, Jia-Feng Yu, Jian-Ming Xie and Xiao Sun*, Prediction of RNA-binding residues in proteins from primary sequence using an enriched random forest model with a novel hybrid feature,Proteins, 79(4), 1230-1239, 2011.(SCI)
8、马昕,郭静,孙啸*,蛋白质中RNA-结合残基预测的随机森林模型,东南大学学报(自然科学版),42(1),50-54,2012. (EI)
9、Hong-De Liu*, Kun Luo, Hao Wen, Xin Ma, Jian-Ming Xie, Xiao Sun, Quantitative analysis reveals increased histone modifications and a broad nucleosome-free region bound by histone acetylases in highly expressed genes in human CD4(+) T cell, Genomics, 101(2), 113-119. 2013. (SCI)
10、 Chang-Chang Cao, Cheng Li, Zheng Huang, Xin Ma and Xiao Sun*, Identifying rare variants with optimal depth of coverage and cost-effective overlapping pool sequencing, Genetic epidemiology, 37(8), 820-30, 2013. (SCI)
11、 刘宏德* , 罗坤 , 马昕,核小体及染色质修饰的基因组分布模式和染色质状态, 生物化学与生物物理进展,40(11): 1088-1099,2013. (SCI)
12、 刘宏德*,张德金,谢建明,袁志栋,马昕,卢志远,龚乐君,孙啸,miRNA基因和编码基因启动子区核小体定位分析,科学通报,2010,55(14),1335-1340. (SCI)
13、 Yang, Yang*, Xin Ma and Jin-Guan Lin., Approximation for the finite-time ruin probability of a general risk model with constant interest rate and extended negatively dependent heavy-tailed claims. Mathematical Problems in Engineering, Article ID 852852, 14 pages, doi:10.1155/2011/852852. (SCI)
14、 Yang, Yang., Jin-Guan Lin, Chao Huang and Xin Ma,The finite-time ruin probability in two non-standard renewal risk models with constant interest rate and dependent subexponential claims. Journal of the Korean Statistical Society, 41, 213-224,2012. (SCI)
15、 Pei-Lin Zhang , Xin Ma , Zhi-Long Peng and Wen-Xin Qin,Monotonicity in the damped pendulum type equations,Zeitschrift fur angewandte Mathematik und Physik (ZAMP), 60(5),823-839,2009. (SCI)
16、 Wen-Xin Qin , Chun-Lan Xu and Xin Ma,Stability of Single-Wave-Form Solutions in the Underdamped Frenkel- Kontorova Model,SIAM Journal on Mathematical Analysis,40(3),952-967,2008. (SCI)
17、 蛋白质-核酸复合物氢键与范德华力作用位点分析,东南大学学报(自然科学版), 41(4), 771-783,2011 (EI)
科研奖励
1. 马昕,2014,江苏省青蓝工程优秀青年骨干教师,江苏省教育厅